Unprecedented Down Syndrome Study Seeks Participants

Awakening Angels | April 9, 2018 

Awakening Angels provides vital funding to unprecedented research aimed at improving the lives of patients with Down syndrome right here in Cleveland, OH.

A collaborative team of medical doctors and psychologists from Case Western Reserve University, University Hospitals and the Cleveland Clinic are working to determine if a medicine called Memantine can improve both memory and thinking in people with Down syndrome.

The only study of it’s kind in the U.S., they’re currently seeking qualified candidates between the ages of 15 and 32.


Memantine is a FDA-approved medication for the treatment of Alzheimer’s Disease, however is not yet approved for persons diagnosed with Down syndrome.

The trial results could change the way we understand the impacts of medications on cognitive and development in people with Down syndrome, ultimately helping them achieve more independence and an enhanced quality of life.


  • The tests, medication and medical care related to the study are provided free of charge
  • Parking will be validated
  • Mileage can be reimbursed for those traveling 20 miles or more


  • Complete five to seven outpatient visits at the University Hospitals in Cleveland, OH
  • Candidates must be 15 to 32 years of age, medically diagnosed with Down syndrome, in good general health and not pregnant
  • Able to swallow medicine capsules (crushing of capsules will not be permitted)
  • Have a reliable caregiver or family member who agrees to come with the participant to all visits, provide information about the participant, and ensure compliance with the medication schedule
  • Speak English or enough to reliably complete the study

To learn more about participating in this study, email melissa.stasko@case.edu or call 216.844.7281.

If you’d like to support this effort, please consider donating (DONATE HERE)  to Awakening Angels where 100 percent of the donations go directly to this study and other initiatives working to create more independence and enhanced quality of life for those affected by Down syndrome and Autism.